Monoclonal Antibodies Vs Vaccines – What Is The Difference

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monoclonal antibodies vs covid vaccines

We all know how a vaccine works. Taken through an injection of an antigen and immune cells generated in response to this injection, later on, helps fight diseases whenever there is exposure. However, monoclonal antibodies are more futuristic and create a different kind of response.

Vaccines and monoclonal antibodies… Sure they might seem similar. Both are used to treat disease. But that’s where the similarities end. We’ll dive deep into their differences in this article.

First, what are monoclonal Antibodies?

Monoclonal antibodies are similar to the natural antibodies produced by the body to help fight and protect against infections. The difference, in this case, is that monoclonal antibodies are artificial and are usually created in a lab and are customized specifically to fight a specific infection.

How do they work especially against Covid-19?

THE FDA recently approved the administration of REGEN-COV or Regeneron (two monoclonal antibodies; Casirivimab and Imdevimab for emergency use). The way this works is that is specifically designed to attack the spike protein of the Covid virus thereby preventing the virus from entering the body’s cells. These two distinct antibodies bind themselves to the virus-cell surface preventing it from infecting other healthy cells.

Trials have shown that monoclonal antibody therapy helps to reduce the risk of death in those that have been infected as well as hospitalization.

What are Vaccines and how do they work?

covid vaccines

A vaccine is often regarded as “active immunity”. Usually, a vaccine is a virus in itself that is no longer active or even a fragment of a virus. The way vaccines work is that it is injected into a person and the person’s immune system reacts to the virus the way it will to an active virus but in this situation, the person won’t fall ill but instead provide the patient with what is regarded as “immune memory.” This is because the body or immune system has learned how to adapt to the virus protecting it from future infection of a particular kind. 

For instance, the SARS-CoV-2 vaccine is like injecting a person with the inactive version of the virus thereby equipping the person with an immune memory of the virus making it possible for the immune system to clear out any active SARS-CoV-2 in the system and prevent it from infecting healthy cells. The immunity provided by vaccines can last for a long time even a lifetime and they are 100% safe. Covid-19 Vaccines can help protect people against contracting the virus and is also effective in the case of patients that are already ill.

Monoclonal antibodies vs vaccines - the difference

Vaccines help to prepare and stimulate the immune system to respond when it is exposed to the virus. According to some experts, the presence of Vaccines in the system is like your immune system having all the needed antibodies required to fight infection before the infections appear.

Monoclonal antibodies on the other hand help to boost the immune system of the already sick person thereby boosting the body’s immune response to infections like Covid-19 to prevent it from getting worse.

One of the major differences between vaccines and monoclonal antibody is the fact that monoclonal antibodies don’t last for long, they don’t last up to 6 months while vaccines learn about the virus and provide longer protection against the virus.

Monoclonal antibody infusion and covid vaccine

Vaccines and monoclonal antibodies are both required to help protect the majority of the population against the devasting effect of Covid-19. While Vaccines are important to help provide the general populace with the required immunity against the virus, monoclonal antibodies are best for those who have already been infected or due to a special condition cannot undergo vaccination. In conclusion, monoclonal antibodies and Covid-19 vaccination together make up essential weapons against the spread of the virus, so we basically cannot have one without the other.

Importance of Monoclonal Antibodies

  • They serve as temporary protection against the virus until a vaccine is available
  • They serve as protection for people who are yet to get the vaccine or have already been exposed to the virus
  • Monoclonal Antibody Infusion is especially good for older adults whose immune system is unable to put up adequate protection against the virus even after vaccination


Is a monoclonal antibody a vaccine?

Monoclonal antibodies are not vaccines rather they are man-made antibodies designed specifically to protect against a virus or a particular infection.

Are monoclonal antibodies used in vaccines?

No, monoclonal antibodies are different from vaccines and are used separately from Vaccines. Monoclonal antibodies are made of man-made antibodies while a vaccine like the Pfizer-BioNTech COVID-19 vaccine is made up of a genetic material that is called a messenger RNA (mRNA). This vaccine contains a synthetic type of messenger RNA whose function is to instruct cells in the body to make a distinctive spike protein of the Covid Virus.

Can you get monoclonal antibody infusion after the covid vaccine?

Yes, you can get monoclonal antibody infusion after the covid vaccine provided you’ve received one or two doses of the vaccine. It’s important to be vaccinated even despite having the monoclonal antibodies in your system to prevent recurrence or future illness. Also, it’s advised to wait 90 days before collecting the vaccine if you’ve already received monoclonal antibody infusion for an illness caused by exposure to Covid-19.

Want to protect your folks from the ravaging pandemic? IV Concierge is the place for you

At IV Concierge, we specialize in delivering injectable medications from the convenience of your own home or office. Our licensed healthcare professionals are the best IV delivery specialists in South Florida & Miami areas. We offer complete protection for you and your loved one, against covid-19 with our antibody infusion therapy.

Concierge services are considered the next generation of healthcare, and we are here to help deliver access to more personalized treatment with more customized care.

As a mobile concierge medical practice, we are proud to see our patients where they are at, It may be in their home or at any place of their choosing.

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