IV Treatment for Depression – What Do You Need To Know

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iv for depression

In this day and age, depression is taking its toll. With more and more people suffering from depression it is now considered a public health issue.


However, most people still think taking pills is the most efficient way to treat depression, but other methods are safer, more effective, and less expensive than taking prescription drugs. And the least expensive of all is IV therapy.


It’s one of the most effective treatments for depression, but very few people are using it. Most people are only aware of two treatment methods for depression: medication and psychotherapy. Sometimes both of these treatments fail, leaving many people with no other conclusion than that they must continue to suffer from the symptoms of severe clinical depression.

In this blog, I aim to answer everything you need to know about the benefits of InfusionTherapy for Depression.

First, what is IV Treatment?

IV therapy was a treatment that has been in use since the 60s and has been the standard for the pain treatment of patients suffering from conditions such as fibromyalgia, stroke-related pain, spinal cord injuries. Iv treatment can also be used for migraine treatment and the process involves the administration of certain nutritious fluids directly into the blood vessels.


In the use of IV treatment for Depression, one particular ingredient that’s key is the use of Ketamine.


Ketamine is an FDA-approved anesthetic that was usually administered to soldiers during the civil war as well as people undergoing surgeries. One key thing about the use of Ketamine is the fact that it doesn’t cause slow breathing & heart rate, hence there is no need for a ventilator when it’s administered.

How does IV Drip for Depression Work?

Often the IV infusion of Ketamine for the treatment of depression is usually used when all other forms of FDA-approved treatment such as oral anti-depressants, psychotherapy, and ECT (Electroconvulsive therapy) fails and the FDA in recent time approved Esketamine for treatment-resistant depression. Esketamine is a form of nasal therapy and its approval was fast-tracked because of the remarkable benefits of Ketamine.


But IV therapy for depression is considered to be one of the common and effective treatments of depression.


How does it work?


It’s important to note that what makes this form of treatment effective, is the way it works. Ketamine derives its antidepressant abilities by acting as a defender against the NMDA receptor. The NMDA receptor is a component that plays an essential role in the way a person’s synapses increase or decrease in activity and that’s why it’s considered a major suspect in situations where nerve cells are damaged or killed as a result of excessive stimulation; a process called excitotoxicity. This particular process is said to be one of the main causes of depression in people and that’s why things like Ketamine that serve as an antagonist to the NMDA receptor preventing excessive stimulation of the synapses can help in the treatment of depression.


Administration of Infusion-based therapy for depression


Usually, in the case of iv treatment for depression, racemic ketamine is administered to the patient intravenously and the treatment is a combination of two identical molecules known as “R” and “S” ketamine. The treatment is usually administered through an IV drip in the arm and takes almost instant effect and the effect doesn’t wear off until weeks after.


Most patients receive six infusions during what is regarded as the induction phase for a duration of two to three weeks. After the induction phase, then there is the maintenance phase where the patient receives one infusion for a duration of two to six weeks.


Also, it’s worthy of note that if a patient fails to respond to treatment after the first six infusions, then it’s unlikely that the patient would respond to any further infusion, so an alternative treatment for depression would have to be prescribed. On the other hand, patients who experience recovery during the infusions will continue to make the treatment effective as it reinforces the effect of the initially administered dose of ketamine.


Another point to note on how IV treatment for depression works is in its side effects. Like every drug, IV therapy for depression has its side effects but the pros outweigh the cons and before it’s administered to a patient, the patient should aware of these side effects. Below are some side-effects of infusion therapy for depression;

  • A feeling of drowsiness
  • Dizziness & blurry vision
  • Loss of appetite and nausea
  • High BP (Blood pressure)
  • Insomnia


Studies have shown that the above-listed side effects are usually mild & temporary and wear off as the patient continues with the treatment and in only very rare cases do patients discontinue treatment as a result of side effects.


Lastly, Ketamine is non-addictive as some portray due to its reputation as a party drug. Ketamine is non-addictive especially when taken in some doses and given the fact that during the treatment for depression, the dose of ketamine is administered by licensed medical personnel the probability of abusing the substance is slim.

Benefits of IV infusion therapy for depression

One of the things that distinguish infusion therapy for depression from other forms of treatment is the time of effectiveness. Unlike most antidepressant treatments which take weeks to have an effect, IV therapy for depression has an almost instant effect on the patient.


So, a patient who is given Ketamine is likely to experience a reduction in suicidal thoughts as well as other depressive symptoms as quickly as possible.


Secondly, studies have shown that IV therapy for depression influences depression in other ways like the reduction of signals that trigger inflammation which causes mood disorders or changes.

Other types of Ketamine therapy for depression

The other type of treatment for depression is the Esketamine nasal spray. This treatment, unlike the IV drip for depression, features only one molecule which is the S molecule and although it has been FDA-approved, there is limited research on its effectiveness for treating depression.

Depression sucks! 

Tired of being depressed, feeling isolated, and having no energy? With our Mobile IV therapy, we bring infused-based treatment for depression to you in the comfort of your home.

At IV Concierge, We make it easy and timely to help you find balance physically and mentally. IV concierge is an upcoming concierge healthcare service that offers FDA-approved intravenous solutions for the treatment of depression for residents in Miami and South Florida.

IV therapy offers a safe, cost-effective alternative to traditional antidepressant medications. Unlike antidepressants, you can receive the benefits of IV therapy for depression in a single session. No need for unpleasant injections or waiting around for weeks on end to begin feeling better. At IV Concierge we offer a variety of services, so you can find the treatment option that best suits your needs and budget.

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